27 January, 2013

New Amyloid Fibril Nomenclature Recommendations Published

In May of 2012, at the XIIIth International Symposium on Amyloidosis in Groningen (Netherlands), the Nomenclature Committee of the International Society of Amyloidosis updated amyloid fibril nomenclature guidelines, and expanded the list of recognized amyloid fibril subtypes. The latter is shown here in 3 tables from the article
From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170

From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170
From Sipe J.D., et al. Amyloid, 2012; 19(4): 167–170

 I wanted to post the Amyloid Fibril Protein Nomenclature List because it serves as a reference for readers, and also provides context for the broad range of medical topics which will be discussed over time in this blog. Keep this post handy!


  1. is it complete?
    because there is no mention of apha-synuclein implicated in PD.

  2. Check again: table III mentions alpha-synuclein as the primary protein in the Lewy bodies of Parkinson's. This particular table list disorders involving misfolded proteins, but not true amyloid fibrils. In Parkinson's disease, Lewy bodies may be found in the substantia nigra, the locus coeruleus, sympathetic ganglia, basal nucleus of Meynert and the cerebral cortex (for a reference describing this which also has a nice picture of a Lewy body, go to